by Brianna Crandall — June 19, 2020 — Researchers at the National Institute of Standards and Technology (NIST) have built an online tool that could help decrease the concentration of aerosols containing the novel coronavirus in the hospital rooms of COVID-19 patients and other spaces such as offices, retail stores and residences, potentially reducing the likelihood of building occupants becoming infected. A second tool described below helps hospitals choose and configure rooms for disinfecting N95 masks for reuse.
Fate and Transport of Indoor Microbiological Aerosols (FaTIMA) tool
The Fate and Transport of Indoor Microbiological Aerosols (FaTIMA) tool considers factors including ventilation, filtration and aerosol properties to estimate the concentration of aerosols a person might encounter in a room. Using the new tool, building managers and engineers can evaluate their options for reducing occupant exposure to the novel coronavirus. A new report serves as a FaTIMA user guide.
The transport of aerosols in spaces such as a hospital room can be simulated using FaTIMA. (Shown: hospital room with nurse and patient, depicting air ducts and filters and a portable air filter) Credit: NIST/B. Hayes
When people breathe, cough and sneeze, they release respiratory droplets and smaller aerosols less than five millionths of a meter in size, explains NIST. Compared with respiratory droplets, the smaller aerosols can remain in the air for longer periods of time. The current data suggest the novel coronavirus is primarily transmitted through contact with larger droplets, but tiny aerosols can also harbor the virus and may pose a threat to people, especially indoors. To establish a sound defense against these aerosols, informed management of airflow and airborne contaminants could be critical.
The researchers leveraged their expertise in developing airflow and contaminant transport models to build FaTIMA, which is based on the NIST software CONTAM, which assesses building ventilation.
Stuart Dols, NIST mechanical engineer and a developer of FaTIMA, noted:
We have been developing CONTAM for decades, and it has been validated and verified for analyzing many aspects of building performance including indoor air quality.
CONTAM has been used to tackle a range of airflow issues in a wide variety of structures. To address the ongoing concern about airborne viruses, Dols used it to build a model of a single room. With FaTIMA, users can set the number of people in the room and the rate at which they exhale aerosols.
For FaTIMA to perform its calculations, the user must provide details about a room’s geometry, ventilation rates, air filter efficiencies and the presence of portable air cleaners, all of which can influence the concentration of small airborne particles to varying degrees.
The tool also requires specifics about the virus-containing aerosols, such as their size and how quickly they deposit onto surfaces. Although the properties of aerosols containing the novel coronavirus are not yet clearly defined, aerosols carrying the more well-studied influenza virus can be modeled in FaTIMA to approximate their behavior.
The users are free to adjust the aerosol property inputs as they see fit, but by default, the values in the tool are based on previous studies of influenza-containing aerosols, which are referenced in the report.
FaTIMA can simulate an individual’s exposure for up to 24 hours even if the person only enters the room periodically, Dols said. In the case of a caregiver scheduled to check on a patient every hour during a 12-hour shift, the tool would be able to predict the person’s average, peak and total exposure in the patient’s room over the course of the entire shift. The tool would also estimate the number of aerosols that had landed on the floors, walls and other surfaces in the room.
Approaches to decrease exposure levels
To find out how to decrease exposure levels for uninfected occupants, several approaches can be taken.
According to Dols:
There are generally three means to reduce exposure to airborne indoor contaminants. You could remove or reduce the source, dilute the room air with clean ventilation or outdoor air, or remove the contaminants using a room air cleaner or local exhaust fan. This tool enables all of these means to be accounted for.
FaTIMA users can vary factors such as ventilation rates, air filter ratings and emission rates (to account for the effects of masks, for example) to identify approaches that reduce aerosol concentrations. Informed by the tool, building managers and engineers can then develop strategies to ventilate effectively and implement them in real buildings, producing a safer environment for occupants such as healthcare workers on the front line.
Both the FaTIMA tool and its associated report are now available on the NIST website.
Tool to help choose and configure rooms for disinfecting N95 masks
In response to the COVID-19 pandemic, hospitals across the United States are disinfecting N95 masks by placing them in repurposed rooms or shipping containers injected with a disinfectant known as vaporized hydrogen peroxide, or VHP, which has previously been used to disinfect isolation rooms after a highly infectious person has left.
NIST spreadsheet can help hospitals determine which rooms are best for disinfecting N95 masks for reuse. Credit: Courtesy of Battelle
Another new tool from NIST can help hospitals and medical professionals determine which rooms should be used to disinfect N95 masks. The tool estimates the amount of VHP masks would receive and suggests that larger rooms containing fewer objects, with less-reactive surfaces and slower ventilation, maintain VHP concentration the best.
Choosing and configuring rooms to house the N95 disinfection processes means accounting for conditions that vary from room to room, such as size, airflow and surface materials. These factors influence VHP concentration and, in certain cases, could prevent masks from receiving effective doses.
By entering important parameters related to a room’s size, materials and ventilation into the spreadsheet, users get estimates of how much VHP would actually deposit onto the masks versus being lost through leaks or absorbed by surfaces. For example, tile floors consume much less VHP than does carpet, which can reduce the VHP concentration in a room by as much as 10 times.
NIST cautions that facilities management (FM), safety professionals and infection control experts need to work together to determine how to apply VHP safely and effectively.
The Tool for Evaluation of Vaporized Hydrogen Peroxide Disinfection of N95 Masks in Small Rooms is available for download from the NIST website.
